Vertex Pharmaceuticals Incorporated (VRTX) — Biotechnology. Numbers-first dossier: valuation, distress risk, calibrated signal.

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VRTX fair-value estimate

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Bid — × — AskUpdated Sep 25, 2026 · 2:42 PM ETVol 748.0K · 3-mo avg 1.40M

Vertex Pharmaceuticals Incorporated (VRTX)

VRTXVertex Pharmaceuticals Incorporatedloading…
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QTick signal
+2net
3 bull / 1 bear factors · balanced
Bull 3 pts·Bear 1 pts30d
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Market context—Sector read · not on fileOKBalance sheet · SafeOKPCE inflation days · ~6% smaller swingsOKNeutral tape · 0/100 · as of 2026-09-25
Smart entry
$519.77
basis · s1 · as of 2026-09-24
Target exit zone
$557–563
center $560.25 · basis · bb upper + high 52w · as of 2026-09-24
Implied move · 1 wk
±$26.57
5.1% · options-priced
Chart pattern
Golden cross
50d above 200d · bullish structure
Pullback risk
Low
0.71× the norm · 47% saw a ≥10% dip · 63d · tape state: neutral
Chart pattern
Golden cross
50d above 200d · bullish structure
Volume vs its own 20-session average0.93×
52-week range$379.72 – $560.25
Below high since 2015-6.8% · $560.25 high
Risk / reward1.13 : 1
Plan stop$496.02
Max pain$517.50 options cluster
RSI 1450.5 fires under 35 · fires near $496.09
Forensic flags1 review
Earnings multiple26.1× fwd · 30.6× trailing
P/E vs its own past80th pctile · 27.5× median
Free cash flow yield2.4% · of market value

Trading in line with its own normal, price up 0.7%. Over the last 20 sessions, 42% of the volume traded on days the stock closed lower.

Entry strategy · 10 triggers

1 of 6 aligned — not yet
RSI 14
●
50.5
fires under 35 · fires near $496.09
vs 50-day
●
$512.75
above the line · fires near $517.63
Bollinger
●
$496.54
no lower pierce · fires near $490.38
VWAP 20
✓
$529.16
below the rolling VWAP
Entry level
●
$519.77
level below · fires near $524.89
Put wall
●
$500.00
2026-09-25 expiry · chain of 2026-09-23
MACD
Context●
-1.32
below zero · rising toward the flip
RVolStatic
0.93×
in line with its own normal
Short int.Static
1.9%
short interest below 20%
ATRStatic
$11.87
14-session average true range
A checklist, not odds on a return: 4 of 6 usable price conditions have to line up. RSI, the 50-day average and the Bollinger band move with the price you set; the 20-day average traded price, the entry level and the busiest put strike stay fixed. MACD, RVol, Short int. and ATR are context only — they never count toward the total.
See the full case→
Next earnings
2026-11-02
in 26 sessions
Next dividend
No indicated yield
no forward dividend on file
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