Protagonist Therapeutics, Inc. (PTGX) — Biotechnology. Numbers-first dossier: valuation, distress risk, calibrated signal.

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Bid — × — AskUpdated Nov 9, 2026 · 4:00 PM ETVol 607.1K · 3-mo avg 638.8K

Protagonist Therapeutics, Inc. (PTGX)

PTGXProtagonist Therapeutics, Inc.loading…
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QTick signal
+4net
3 bull / 1 bear factors · leaning
Bull 5 pts·Bear 1 pts30d
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Market context—Sector read · not on fileOKBalance sheet · Safe—Inflation-report days · not on fileOKCalm trading · sharp-drop risk 3/100 · Nov 9
$135.22
near a recent low and a support level · Nov 9
$139–142
near a resistance level, a round-number price, the 50-day average and the 50-day average trade price · midpoint $140.45 · Nov 9
±$0.30
±0.2% up or down, priced by the options market
Golden cross
50-day average is above the 200-day — an uptrend
In line
85% of similar setups fell 10% or more within 3 months · 1.1× the usual rate · rating eased: at bottom zone (0/6 bottoming checks met)
Golden cross
50-day average is above the 200-day — an uptrend
Trading volume9% below normal0.91× its 20-day average
Past year's range$73.84 – $160.81lowest to highest price
From its peak15.5% belowpeak $160.81, highest since 2016
Gain vs. risk0.37 to 1$0.37 possible gain per $1 at risk
Plan fails below$123.74the setup is broken under this price
Options pressure point$115.00price can drift here near expiry
Momentum (RSI)45.1fires under 35 · fires near $125.71
Accounting warning signs1worth checking — see the list
Price vs. profit131.9× last 12 monthsa loss is expected next year
Price vs. its own pastpricier than 100%of the last 5 years · usual P/E 16.0×
Cash it generates0.6%of its market value, per year

Last session traded in line with its own normal, price up 2.9%. Over the last 20 sessions, 38% of the volume traded on days the stock closed lower.

Entry strategy · 10 triggers

3 of 6 aligned — closing in
RSI 14
●
45.1
fires under 35 · fires near $125.71
vs 50-day
✓
$141.35
below the line
Bollinger
●
$130.55
no lower pierce · fires near $129.02
VWAP 20
✓
$138.20
below the rolling VWAP
Entry level
✓
$135.22
within 1% of model level
Put wall
●
$95.00
2026-11-20 expiry · chain of 2026-11-09
MACD
Context✓
+0.22
histogram above zero · rising
RVolStatic
0.91×
in line with its own normal
Short int.Static
19.6%
short interest below 20%
ATRStatic
$5.74
14-session average true range
A checklist, not odds on a return: 4 of 6 usable price conditions have to line up. RSI, the 50-day average and the Bollinger band move with the price you set; the 20-day average traded price, the entry level and the busiest put strike stay fixed. MACD, RVol, Short int. and ATR are context only — they never count toward the total.
See the full case→
Next earnings
2027-02-25
in 73 sessions
Next dividend
No indicated yield
no forward dividend on file