Denali Therapeutics Inc. (DNLI) — Biotechnology. Numbers-first dossier: valuation, distress risk, calibrated signal.

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Bid — × — AskUpdated Nov 6, 2026 · 4:00 PM ETVol 1.59M · 3-mo avg 1.63M

Denali Therapeutics Inc. (DNLI)

DNLIDenali Therapeutics Inc.loading…
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QTick signal
-2net
2 bull / 3 bear factors · balanced
Bull 3 pts·Bear 5 pts30d
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Market context—Sector read · not on fileOKBalance sheet · Safe—Inflation-report days · not on fileOKCalm trading · sharp-drop risk 0/100 · Nov 6
$19.97
near a recent low and a support level · Nov 6
$21.26
near a round-number price and the 200-day average · midpoint $21.26 · Nov 6
±$2.82
±14.0% up or down, priced by the options market
Death cross
50-day average is below the 200-day — a downtrend
In line
95% of similar setups fell 10% or more within 3 months · 1.2× the usual rate · rating eased: at bottom zone (2/6 bottoming checks met)
Death cross
50-day average is below the 200-day — a downtrend
Trading volume13% below normal0.87× its 20-day average
Past year's range$15.18 – $27.30lowest to highest price
From its peak79.1% belowpeak $96.12, highest since 2017
Gain vs. risk0.62 to 1$0.62 possible gain per $1 at risk
Plan fails below$18.14the setup is broken under this price
Options pressure point$17.50price can drift here near expiry
Momentum (RSI)54.1fires under 35 · fires near $16.56
Accounting warning signs1worth checking — see the list
Price vs. profitno profit to compare
Price vs. its own pastusual P/E 181.8×median of the last 5 years
Cash it generates-13.1%it used more cash than it made

Last session traded in line with its own normal, price up 1.8%. Over the last 20 sessions, 45% of the volume traded on days the stock closed lower.

Entry strategy · 10 triggers

2 of 5 aligned — closing in
RSI 14
●
54.1
fires under 35 · fires near $16.56
vs 50-day
✓
$20.16
at the line
Bollinger
●
$17.41
no lower pierce · fires near $17.16
VWAP 20
●
$19.08
above the rolling VWAP · fires near $19.06
Entry level
✓
$19.97
within 1% of model level
Put wall
●
—
not on file
MACD
Context✓
+0.28
histogram above zero · fading
RVolStatic
0.87×
in line with its own normal
Short int.Static
10.7%
short interest below 20%
ATRStatic
$0.91
14-session average true range
A checklist, not odds on a return: 3 of 5 usable price conditions have to line up. RSI, the 50-day average and the Bollinger band move with the price you set; the 20-day average traded price, the entry level and the busiest put strike stay fixed. MACD, RVol, Short int. and ATR are context only — they never count toward the total.
See the full case→
Next earnings
2026-11-05
reported last session · reaction session open
Next dividend
No indicated yield
no forward dividend on file